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CMap Candidate Details

Structure:
CMap ID: C03540
Pert ID: BRD-K60690191
Compound Name: MPEP
Targets: GRM1|GRM4|GRM5
MoA: glutamate receptor antagonist
SMILES: Cc1cccc(n1)C#Cc1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
44424 BRD-K60690191 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44600 BRD-K60690191 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44996 BRD-K60690191 ASC 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.97
45288 BRD-K60690191 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45552 BRD-K60690191 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45708 BRD-K60690191 MCF??7.00 10 uM 24 h 0.29 1.2 0.43 0.0 0.0 0.0
46425 BRD-K60690191 PHH 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
46751 BRD-K60690191 SKB 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
98153 BRD-K60690191 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98410 BRD-K60690191 NEU 10 uM 24 h 0.18 0.74 0.0 -0.25 -0.83 0.16
99284 BRD-K60690191 U2OS 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).