CMap Candidate Details
Structure:
| CMap ID: | C03626 |
| Pert ID: | BRD-K02953697 |
| Compound Name: | naringin |
| Targets: | SLCO1A2 |
| MoA: | cytochrome P450 inhibitor |
| SMILES: | C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6718 | BRD-K02953697 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7132 | BRD-K02953697 | A549 | 10 uM | 6 h | -0.19 | -0.8 | 0.0 | 0.23 | 0.82 | 0.11 |
| 7288 | BRD-K02953697 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7828 | BRD-K02953697 | HT29 | 10 uM | 24 h | -0.26 | -1.07 | 0.28 | 0.0 | 0.0 | 0.0 |
| 8237 | BRD-K02953697 | MCF??7.00 | 10 uM | 6 h | 0.18 | 0.74 | 0.0 | 0.27 | 0.96 | 0.33 |
| 8343 | BRD-K02953697 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8796 | BRD-K02953697 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.5 |