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CMap Candidate Details

Structure:
CMap ID: C03649
Pert ID: BRD-K65678996
Compound Name: nefiracetam
Targets: CHRM1
MoA: acetylcholine receptor agonist; benzodiazepine receptor agonist
SMILES: Cc1cccc(C)c1NC(=O)CN1CCCC1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124942 BRD-K65678996 A375 0.04 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
125117 BRD-K65678996 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125135 BRD-K65678996 PC3 0.125 uM 24 h -0.34 -1.44 1.43 -0.27 -0.9 0.29
125175 BRD-K65678996 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125216 BRD-K65678996 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
133000 BRD-K65678996 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133016 BRD-K65678996 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
133063 BRD-K65678996 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
133095 BRD-K65678996 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133125 BRD-K65678996 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133170 BRD-K65678996 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
133205 BRD-K65678996 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133233 BRD-K65678996 MCF??7.00 0.25 uM 24 h 0.3 1.25 0.56 -0.25 -0.83 0.17
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).