CMap Candidate Details
Structure:
| CMap ID: | C03666 |
| Pert ID: | BRD-K79989959 |
| Compound Name: | nesbuvir |
| Targets: | |
| MoA: | RNA polymerase inhibitor |
| SMILES: | CNC(=O)c1c(oc2cc(N(CCO)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127376 | BRD-K79989959 | A375 | 0.04 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.0 | 0.0 | 0.0 |
| 127453 | BRD-K79989959 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.96 | 0.34 |
| 127480 | BRD-K79989959 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.39 | 1.38 | 2.17 |
| 127544 | BRD-K79989959 | JURKAT | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.12 |
| 127631 | BRD-K79989959 | PC3 | 0.04 uM | 24 h | 0.25 | 1.04 | 0.16 | 0.29 | 1.02 | 0.49 |
| 127717 | BRD-K79989959 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135355 | BRD-K79989959 | A549 | 0.74 uM | 24 h | 0.16 | 0.65 | 0.0 | -0.28 | -0.95 | 0.4 |
| 135423 | BRD-K79989959 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135457 | BRD-K79989959 | MCF10A | 0.01 uM | 24 h | 0.29 | 1.23 | 0.49 | -0.23 | -0.78 | 0.09 |
| 135487 | BRD-K79989959 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135512 | BRD-K79989959 | THP1 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |