CMap Candidate Details
Structure:
| CMap ID: | C03671 |
| Pert ID: | BRD-K15502390 |
| Compound Name: | nevirapine |
| Targets: | CYP1A2|CYP2A6|CYP2B6|CYP2C9|CYP2D6|CYP3A4|CYP3A5 |
| MoA: | non-nucleoside reverse transcriptase inhibitor |
| SMILES: | Cc1ccnc2c1NC(=O)c1cccnc1N2C1CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25492 | BRD-K15502390 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96641 | BRD-K15502390 | A375 | 3.33 uM | 24 h | -0.3 | -1.23 | 0.63 | 0.32 | 1.13 | 0.82 |
| 120259 | BRD-K15502390 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120391 | BRD-K15502390 | MCF??7.00 | 10 uM | 24 h | -0.23 | -0.94 | 0.08 | 0.0 | 0.0 | 0.0 |
| 120452 | BRD-K15502390 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128900 | BRD-K15502390 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128916 | BRD-K15502390 | HELA | 0.74 uM | 24 h | -0.24 | -0.99 | 0.13 | -0.36 | -1.21 | 1.24 |
| 128933 | BRD-K15502390 | HT29 | 0.08 uM | 24 h | 0.26 | 1.09 | 0.23 | 0.0 | 0.0 | 0.0 |
| 128966 | BRD-K15502390 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.9 |