CMap Candidate Details
Structure:
| CMap ID: | C03681 |
| Pert ID: | BRD-K60237333 |
| Compound Name: | niacin |
| Targets: | DGAT2|HCAR1|HCAR2|HCAR3|NNMT|QPRT |
| MoA: | NAD precursor; vitamin B |
| SMILES: | OC(=O)c1cccnc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 53406 | BRD-K60237333 | HEPG2 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53597 | BRD-K60237333 | HUH7 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53678 | BRD-K60237333 | PHH | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123812 | BRD-K60237333 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |
| 123852 | BRD-K60237333 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.25 |
| 123921 | BRD-K60237333 | HEK293 | 1.11 uM | 24 h | 0.25 | 1.04 | 0.15 | 0.0 | 0.0 | 0.0 |
| 124023 | BRD-K60237333 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124074 | BRD-K60237333 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.54 |
| 124140 | BRD-K60237333 | MDAMB231 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 124156 | BRD-K60237333 | PC3 | 3.33 uM | 24 h | -0.27 | -1.12 | 0.38 | 0.0 | 0.0 | 0.0 |
| 124204 | BRD-K60237333 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124257 | BRD-K60237333 | YAPC | 1.11 uM | 24 h | 0.21 | 0.86 | 0.01 | 0.0 | 0.0 | 0.0 |
| 132178 | BRD-K60237333 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 132208 | BRD-K60237333 | HELA | 2.22 uM | 24 h | 0.27 | 1.14 | 0.32 | 0.0 | 0.0 | 0.0 |
| 132242 | BRD-K60237333 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.1 |
| 132265 | BRD-K60237333 | MCF??7.00 | 0.01 uM | 24 h | -0.23 | -0.96 | 0.1 | -0.27 | -0.9 | 0.28 |