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CMap Candidate Details

Structure:
CMap ID: C03686
Pert ID: BRD-K76810206
Compound Name: nicergoline
Targets: ADRA1A
MoA: adrenergic receptor antagonist
SMILES: CO[C@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5364 BRD-K76810206 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5801 BRD-K76810206 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6589 BRD-K76810206 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39763 BRD-K76810206 ASC 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
40056 BRD-K76810206 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
40320 BRD-K76810206 HT29 10 uM 6 h 0.0 0.0 0.0 0.19 0.66 0.01
40864 BRD-K76810206 NEU 10 uM 24 h -0.21 -0.88 0.03 -0.34 -1.14 1.01
41181 BRD-K76810206 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.22
41520 BRD-K76810206 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91045 BRD-K76810206 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99486 BRD-K76810206 U2OS 4 uM 6 h 0.26 1.1 0.24 0.2 0.7 0.02
127022 BRD-K76810206 A375 0.04 uM 24 h -0.3 -1.26 0.72 -0.23 -0.78 0.09
127070 BRD-K76810206 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127185 BRD-K76810206 MCF10A 3.33 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
127243 BRD-K76810206 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127318 BRD-K76810206 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135046 BRD-K76810206 A549 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
135131 BRD-K76810206 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135175 BRD-K76810206 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135230 BRD-K76810206 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
135270 BRD-K76810206 MDAMB231 0.03 uM 24 h 0.25 1.03 0.14 -0.24 -0.81 0.13
135309 BRD-K76810206 THP1 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).