CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03694
Pert ID:	BRD-K96354014
Compound Name:	nifedipine
Targets:	CACNA1C\|CACNA1D\|CACNA1F\|CACNA1H\|CACNA1S\|CACNA2D1\|CACNB2\|CALM1\|GLRA1\|GLRA3\|GLRB\|KCNA1\|KCNA5\|NR1I2\|TRPM3
MoA:	calcium channel blocker
SMILES:	COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
9011	BRD-K96354014	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
9131	BRD-K96354014	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
9554	BRD-K96354014	AGS	10 uM	6 h	0.0	0.0	0.0	0.3	1.07	0.64
9862	BRD-K96354014	H1299	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10099	BRD-K96354014	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10331	BRD-K96354014	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10637	BRD-K96354014	HCT116	10 uM	6 h	-0.24	-0.98	0.12	0.23	0.83	0.11
11310	BRD-K96354014	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.21	0.76	0.05
11623	BRD-K96354014	NCIH2073	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11880	BRD-K96354014	NCIH508	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12416	BRD-K96354014	NOMO1	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13059	BRD-K96354014	THP1	10 uM	6 h	0.23	0.95	0.06	0.27	0.95	0.32
13403	BRD-K96354014	U937	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13712	BRD-K96354014	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45056	BRD-K96354014	ASC	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.13	0.97
46165	BRD-K96354014	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46809	BRD-K96354014	SKB	10 uM	24 h	0.0	0.0	0.0	-0.4	-1.36	2.02
52875	BRD-K96354014	HEPG2	40 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
53090	BRD-K96354014	MCF10A	100 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.25
91033	BRD-K96354014	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
96024	BRD-K96354014	PHH	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117537	BRD-K96354014	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117618	BRD-K96354014	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary