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CMap Candidate Details

Structure:
CMap ID: C00370
Pert ID: BRD-K20001883
Compound Name: apabetalone
Targets: BRD3
MoA: apolipoprotein expression enhancer
SMILES: COc1cc(OC)c2c(c1)[nH]c(nc2=O)-c1cc(C)c(OCCO)c(C)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90297 BRD-K20001883 VCAP 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
118718 BRD-K20001883 A549 1.11 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
118794 BRD-K20001883 HCC515 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118836 BRD-K20001883 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121406 BRD-K20001883 HELA 10 uM 24 h 0.24 1.0 0.1 -0.31 -1.05 0.7
121460 BRD-K20001883 MCF??7.00 10 uM 24 h 0.3 1.24 0.51 0.0 0.0 0.0
121478 BRD-K20001883 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
121510 BRD-K20001883 YAPC 10 uM 24 h 0.41 1.72 1.71 0.0 0.0 0.0
129404 BRD-K20001883 A375 2.22 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
129434 BRD-K20001883 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129490 BRD-K20001883 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).