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CMap Candidate Details

Structure:
CMap ID: C03707
Pert ID: BRD-K76775527
Compound Name: nimesulide
Targets: LTF|PLA2G2E|PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3259 BRD-K76775527 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3980 BRD-K76775527 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.38 2.02
39762 BRD-K76775527 ASC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
40055 BRD-K76775527 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40863 BRD-K76775527 NEU 10 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
41180 BRD-K76775527 NPC 10 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
41519 BRD-K76775527 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
90929 BRD-K76775527 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99484 BRD-K76775527 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127024 BRD-K76775527 A375 10 uM 24 h -0.22 -0.94 0.07 0.0 0.0 0.0
127072 BRD-K76775527 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127106 BRD-K76775527 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127142 BRD-K76775527 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127246 BRD-K76775527 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135049 BRD-K76775527 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135087 BRD-K76775527 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.49
135177 BRD-K76775527 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135210 BRD-K76775527 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
135233 BRD-K76775527 MCF??7.00 0.01 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
135273 BRD-K76775527 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135311 BRD-K76775527 THP1 0.74 uM 24 h -0.26 -1.08 0.31 0.0 0.0 0.0
135328 BRD-K76775527 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).