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CMap Candidate Details

Structure:
CMap ID: C03731
Pert ID: BRD-K84011460
Compound Name: nizofenone
Targets:
MoA: ion channel antagonist
SMILES: CCN(CC)Cc1nccn1-c1ccc(cc1C(=O)c1ccccc1Cl)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125580 BRD-K84011460 A375 0.04 uM 24 h -0.23 -0.98 0.12 0.0 0.0 0.0
125613 BRD-K84011460 A549 10 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
125650 BRD-K84011460 HEK293 0.04 uM 24 h -0.23 -0.98 0.12 -0.43 -1.44 15.35
125731 BRD-K84011460 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125801 BRD-K84011460 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125827 BRD-K84011460 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125929 BRD-K84011460 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133697 BRD-K84011460 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133763 BRD-K84011460 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
133796 BRD-K84011460 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133823 BRD-K84011460 JURKAT 0.74 uM 24 h 0.26 1.1 0.24 -0.36 -1.21 1.22
133913 BRD-K84011460 MDAMB231 2.22 uM 24 h 0.23 0.97 0.08 -0.3 -1.01 0.57
133942 BRD-K84011460 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133977 BRD-K84011460 THP1 0.03 uM 24 h 0.29 1.23 0.5 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).