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CMap Candidate Details

Structure:
CMap ID: C03742
Pert ID: BRD-K85015012
Compound Name: NNC-05-2090
Targets: SLC6A12
MoA: GABA uptake inhibitor; GAT inhibitor
SMILES: COc1ccccc1C1(O)CCN(CCCn2c3ccccc3c3ccccc23)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1788 BRD-K85015012 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1993 BRD-K85015012 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.82
2702 BRD-K85015012 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39354 BRD-K85015012 A549 10 uM 24 h 0.22 0.92 0.04 0.26 0.91 0.23
39796 BRD-K85015012 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
40088 BRD-K85015012 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40352 BRD-K85015012 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.19 1.01
40648 BRD-K85015012 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40895 BRD-K85015012 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41216 BRD-K85015012 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41555 BRD-K85015012 SKB 10 uM 24 h 0.0 0.0 0.0 0.4 1.41 2.18
97137 BRD-K85015012 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97204 BRD-K85015012 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).