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CMap Candidate Details

Structure:
CMap ID: C03743
Pert ID: BRD-K78122587
Compound Name: NNC-55-0396
Targets: CATSPER1|CATSPER2|CATSPER3|CATSPER4
MoA: T-type calcium channel blocker
SMILES: CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C1CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4254 BRD-K78122587 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4491 BRD-K78122587 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4824 BRD-K78122587 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39176 BRD-K78122587 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39344 BRD-K78122587 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39765 BRD-K78122587 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40059 BRD-K78122587 HEPG2 10 uM 6 h 0.3 1.24 0.53 0.0 0.0 0.0
40322 BRD-K78122587 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40505 BRD-K78122587 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
41522 BRD-K78122587 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
88141 BRD-K78122587 VCAP 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
99506 BRD-K78122587 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).