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CMap Candidate Details

Structure:
CMap ID: C03765
Pert ID: BRD-A14886633
Compound Name: norgestrel
Targets: PGR
MoA: progesterone receptor agonist
SMILES: CC[C@]12CCC3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122266 BRD-A14886633 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122371 BRD-A14886633 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122424 BRD-A14886633 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122489 BRD-A14886633 THP1 10 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
130567 BRD-A14886633 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130600 BRD-A14886633 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130634 BRD-A14886633 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130678 BRD-A14886633 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130719 BRD-A14886633 HT29 2.22 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
130765 BRD-A14886633 MCF??7.00 0.74 uM 24 h 0.28 1.19 0.41 0.0 0.0 0.0
130818 BRD-A14886633 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130844 BRD-A14886633 YAPC 0.01 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).