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CMap Candidate Details

Structure:
CMap ID: C00378
Pert ID: BRD-K85140930
Compound Name: aphidicolin
Targets:
MoA: RNA synthesis inhibitor
SMILES: C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1C[C@@H]3C[C@]21CC[C@]3(O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124391 BRD-K85140930 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124432 BRD-K85140930 JURKAT 3.33 uM 24 h -0.25 -1.05 0.23 0.33 1.18 0.98
124495 BRD-K85140930 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
124525 BRD-K85140930 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132338 BRD-K85140930 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132367 BRD-K85140930 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132397 BRD-K85140930 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
132431 BRD-K85140930 HEK293 2.22 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
132448 BRD-K85140930 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132504 BRD-K85140930 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
132533 BRD-K85140930 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132620 BRD-K85140930 THP1 2.22 uM 24 h -0.16 -0.67 0.0 0.3 1.07 0.63
132648 BRD-K85140930 YAPC 2.22 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).