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CMap Candidate Details

Structure:
CMap ID: C03802
Pert ID: BRD-K74371986
Compound Name: NSI-189
Targets:
MoA: neurotrophic agent
SMILES: CC(C)CCNc1ncccc1C(=O)N1CCN(Cc2ccccc2)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127012 BRD-K74371986 A375 1.11 uM 24 h 0.3 1.27 0.58 0.0 0.0 0.0
127092 BRD-K74371986 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127204 BRD-K74371986 MCF??7.00 0.04 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
127231 BRD-K74371986 PC3 0.04 uM 24 h -0.29 -1.22 0.62 0.0 0.0 0.0
127274 BRD-K74371986 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135034 BRD-K74371986 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135077 BRD-K74371986 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
135100 BRD-K74371986 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.2
135145 BRD-K74371986 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 1.92
135164 BRD-K74371986 JURKAT 0.01 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
135199 BRD-K74371986 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135253 BRD-K74371986 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135323 BRD-K74371986 YAPC 0.74 uM 24 h -0.24 -0.99 0.14 -0.34 -1.16 1.1
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).