CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03805
Pert ID:	BRD-K54708045
Compound Name:	nTZDpa
Targets:	PPARG
MoA:	PPAR receptor agonist
SMILES:	OC(=O)c1n(Cc2ccc(Cl)cc2)c2ccc(Cl)cc2c1Sc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1759	BRD-K54708045	HA1E	10 uM	6 h	0.0	0.0	0.0	-0.26	-0.86	0.22
1925	BRD-K54708045	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2167	BRD-K54708045	PC3	10 uM	24 h	0.0	0.0	0.0	0.42	1.49	2.26
2467	BRD-K54708045	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41791	BRD-K54708045	A375	10 uM	6 h	-0.31	-1.29	0.77	-0.29	-0.99	0.5
42109	BRD-K54708045	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42396	BRD-K54708045	ASC	10 uM	24 h	0.0	0.0	0.0	0.25	0.88	0.18
42715	BRD-K54708045	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43016	BRD-K54708045	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43330	BRD-K54708045	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.3	1.05	0.58
43581	BRD-K54708045	NPC	10 uM	24 h	0.22	0.9	0.02	-0.2	-0.66	0.01
43884	BRD-K54708045	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44141	BRD-K54708045	SKB	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.65
53246	BRD-K54708045	MCF10A	15 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99661	BRD-K54708045	U2OS	10 uM	6 h	0.0	0.0	0.0	0.22	0.77	0.06

Summary