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CMap Candidate Details

Structure:
CMap ID: C03819
Pert ID: BRD-K79259477
Compound Name: NVP-BHG712
Targets: EPHB4
MoA: ephrin inhibitor
SMILES: Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94414 BRD-K79259477 A375 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.05
94446 BRD-K79259477 A549 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
94482 BRD-K79259477 ASC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94550 BRD-K79259477 CD34 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
94597 BRD-K79259477 HCC515 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.92
94641 BRD-K79259477 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94691 BRD-K79259477 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94745 BRD-K79259477 HME1 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
94792 BRD-K79259477 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94837 BRD-K79259477 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
94890 BRD-K79259477 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.05
94936 BRD-K79259477 MCF10A 10 uM 24 h -0.26 -1.09 0.32 0.22 0.77 0.06
94975 BRD-K79259477 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
95016 BRD-K79259477 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95054 BRD-K79259477 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
95117 BRD-K79259477 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95163 BRD-K79259477 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
95209 BRD-K79259477 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95273 BRD-K79259477 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).