CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03876
Pert ID:	BRD-K78485176
Compound Name:	olmesartan-medoxomil
Targets:	AGTR1
MoA:	angiotensin receptor antagonist
SMILES:	CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5803	BRD-K78485176	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5956	BRD-K78485176	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6591	BRD-K78485176	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37740	BRD-K78485176	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38556	BRD-K78485176	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91098	BRD-K78485176	HUH7	6.66 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
95421	BRD-K78485176	U2OS	10 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
127032	BRD-K78485176	A375	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127052	BRD-K78485176	HA1E	0.04 uM	24 h	0.0	0.0	0.0	-0.24	-0.82	0.15
127116	BRD-K78485176	HELA	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127151	BRD-K78485176	HT29	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127220	BRD-K78485176	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127254	BRD-K78485176	PC3	0.04 uM	24 h	0.0	0.0	0.0	-0.35	-1.19	1.15
127292	BRD-K78485176	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127327	BRD-K78485176	YAPC	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135059	BRD-K78485176	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135116	BRD-K78485176	HEK293	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135186	BRD-K78485176	JURKAT	0.08 uM	24 h	0.25	1.04	0.16	0.37	1.3	1.59
135218	BRD-K78485176	MCF10A	0.03 uM	24 h	0.27	1.11	0.26	0.0	0.0	0.0
135284	BRD-K78485176	MDAMB231	0.08 uM	24 h	0.32	1.32	0.79	0.0	0.0	0.0

Summary