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CMap Candidate Details

Structure:
CMap ID: C03891
Pert ID: BRD-A55962179
Compound Name: omeprazole
Targets: ATP4A|CLCN2
MoA: ATPase inhibitor
SMILES: COc1ccc2nc([nH]c2c1)S(=O)Cc1ncc(C)c(OC)c1C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4313 BRD-A55962179 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
22205 BRD-A55962179 A549 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
24083 BRD-A55962179 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37522 BRD-A55962179 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37833 BRD-A55962179 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38371 BRD-A55962179 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38649 BRD-A55962179 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53278 BRD-A55962179 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90789 BRD-A55962179 HPTEC 100 uM 6 h 0.23 0.96 0.07 -0.39 -1.3 1.6
91294 BRD-A55962179 HUH7 10 uM 72 h 0.26 1.1 0.24 0.0 0.0 0.0
123554 BRD-A55962179 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
123757 BRD-A55962179 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131968 BRD-A55962179 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132004 BRD-A55962179 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132027 BRD-A55962179 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132055 BRD-A55962179 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132069 BRD-A55962179 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
132100 BRD-A55962179 PC3 2.22 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).