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CMap Candidate Details

Structure:
CMap ID: C00400
Pert ID: BRD-K67860401
Compound Name: AR-A014418
Targets: GSK3B
MoA: glycogen synthase kinase inhibitor
SMILES: COc1ccc(CNC(=O)Nc2ncc(s2)[N+]([O-])=O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1770 BRD-K67860401 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1949 BRD-K67860401 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2162 BRD-K67860401 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2461 BRD-K67860401 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41828 BRD-K67860401 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41971 BRD-K67860401 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
42445 BRD-K67860401 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43057 BRD-K67860401 HT29 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.36 2.02
43347 BRD-K67860401 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.12
44180 BRD-K67860401 SKB 10 uM 24 h 0.17 0.71 0.0 0.29 1.03 0.5
53469 BRD-K67860401 HEPG2 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53529 BRD-K67860401 HUH7 10 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
53685 BRD-K67860401 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
95859 BRD-K67860401 NPC 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95928 BRD-K67860401 YAPC 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99077 BRD-K67860401 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99376 BRD-K67860401 U2OS 15 uM 6 h 0.28 1.16 0.34 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).