CMap Candidate Details
Structure:
| CMap ID: | C04012 |
| Pert ID: | BRD-K08924299 |
| Compound Name: | palonosetron |
| Targets: | HTR3A |
| MoA: | serotonin receptor antagonist |
| SMILES: | O=C1N(C[C@H]2CCCc3cccc1c23)[C@@H]1CN2CCC1CC2 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 22240 | BRD-K08924299 | A549 | 10 uM | 6 h | -0.16 | -0.68 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22695 | BRD-K08924299 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22978 | BRD-K08924299 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24116 | BRD-K08924299 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.87 |
| 121147 | BRD-K08924299 | A375 | 0.125 uM | 24 h | -0.26 | -1.09 | 0.32 | 0.0 | 0.0 | 0.0 |
| 121220 | BRD-K08924299 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121267 | BRD-K08924299 | HELA | 0.37 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121277 | BRD-K08924299 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129329 | BRD-K08924299 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.86 | 0.2 |
| 129351 | BRD-K08924299 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.11 |
| 129367 | BRD-K08924299 | YAPC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.93 | 0.34 |