CMap Candidate Details
Structure:
| CMap ID: | C04045 |
| Pert ID: | BRD-K66412701 |
| Compound Name: | pazufloxacin |
| Targets: | |
| MoA: | topoisomerase inhibitor |
| SMILES: | C[C@H]1COc2c(c(F)cc3c2n1cc(C(O)=O)c3=O)C1(N)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25406 | BRD-K66412701 | VCAP | 10 uM | 24 h | -0.21 | -0.89 | 0.03 | 0.34 | 1.2 | 1.1 |
| 91330 | BRD-K66412701 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124945 | BRD-K66412701 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.1 | 0.68 |
| 124979 | BRD-K66412701 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.52 |
| 125008 | BRD-K66412701 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125040 | BRD-K66412701 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.79 |
| 125059 | BRD-K66412701 | HT29 | 10 uM | 24 h | 0.23 | 0.95 | 0.07 | 0.0 | 0.0 | 0.0 |
| 125081 | BRD-K66412701 | MCF10A | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.76 | 0.08 |
| 125122 | BRD-K66412701 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125180 | BRD-K66412701 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 133070 | BRD-K66412701 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.32 |
| 133177 | BRD-K66412701 | JURKAT | 0.08 uM | 24 h | 0.2 | 0.85 | 0.01 | 0.0 | 0.0 | 0.0 |
| 133239 | BRD-K66412701 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.66 | 0.01 |
| 133299 | BRD-K66412701 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133323 | BRD-K66412701 | YAPC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.91 |