CMap Candidate Details
Structure:
| CMap ID: | C04050 |
| Pert ID: | BRD-K52721684 |
| Compound Name: | PCO-400 |
| Targets: | KCNJ8 |
| MoA: | potassium channel activator |
| SMILES: | CC1(C)Oc2ccc(cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O)C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2898 | BRD-K52721684 | HA1E | 10 uM | 24 h | 0.19 | 0.81 | 0.0 | 0.25 | 0.89 | 0.2 |
| 3227 | BRD-K52721684 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3630 | BRD-K52721684 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.07 |
| 3968 | BRD-K52721684 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 41786 | BRD-K52721684 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42103 | BRD-K52721684 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.11 |
| 42387 | BRD-K52721684 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.19 |
| 43010 | BRD-K52721684 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43201 | BRD-K52721684 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.29 |
| 43574 | BRD-K52721684 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43875 | BRD-K52721684 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.94 | 0.28 |
| 99640 | BRD-K52721684 | U2OS | 15 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |