CMap Candidate Details
Structure:
| CMap ID: | C04054 |
| Pert ID: | BRD-K34713073 |
| Compound Name: | PD-123319 |
| Targets: | AGTR2 |
| MoA: | angiotensin antagonist |
| SMILES: | CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120569 | BRD-K34713073 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120607 | BRD-K34713073 | HA1E | 1.11 uM | 24 h | -0.25 | -1.05 | 0.24 | -0.2 | -0.67 | 0.02 |
| 120674 | BRD-K34713073 | HT29 | 0.37 uM | 24 h | 0.31 | 1.28 | 0.64 | 0.0 | 0.0 | 0.0 |
| 120727 | BRD-K34713073 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120786 | BRD-K34713073 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120835 | BRD-K34713073 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128991 | BRD-K34713073 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129023 | BRD-K34713073 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129062 | BRD-K34713073 | MCF??7.00 | 0.03 uM | 24 h | 0.23 | 0.97 | 0.08 | 0.0 | 0.0 | 0.0 |