CMap Candidate Details
Structure:
| CMap ID: | C04056 |
| Pert ID: | BRD-K26603252 |
| Compound Name: | PD-153035 |
| Targets: | EGFR|KDR |
| MoA: | EGFR inhibitor |
| SMILES: | COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119936 | BRD-K26603252 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119974 | BRD-K26603252 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120019 | BRD-K26603252 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120044 | BRD-K26603252 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.71 | 0.02 |
| 120091 | BRD-K26603252 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120135 | BRD-K26603252 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.26 |
| 120176 | BRD-K26603252 | PC3 | 0.04 uM | 24 h | -0.2 | -0.85 | 0.01 | 0.0 | 0.0 | 0.0 |
| 120209 | BRD-K26603252 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |