CMap Candidate Details
Structure:
| CMap ID: | C04064 |
| Pert ID: | BRD-K17702546 |
| Compound Name: | PD-168393 |
| Targets: | EGFR|ERBB2|SRC |
| MoA: | EGFR inhibitor |
| SMILES: | Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 117341 | BRD-K17702546 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 117381 | BRD-K17702546 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117419 | BRD-K17702546 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.76 | 0.07 |
| 117464 | BRD-K17702546 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117511 | BRD-K17702546 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117555 | BRD-K17702546 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.07 |
| 117596 | BRD-K17702546 | MCF??7.00 | 10 uM | 24 h | 0.18 | 0.75 | 0.0 | -0.3 | -1.0 | 0.52 |
| 117634 | BRD-K17702546 | PC3 | 10 uM | 24 h | 0.17 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 |