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CMap Candidate Details

Structure:
CMap ID: C04071
Pert ID: BRD-K82823804
Compound Name: PD-407824
Targets: WEE1
MoA: PKC inhibitor
SMILES: Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1785 BRD-K82823804 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
2132 BRD-K82823804 HCC515 10 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
2432 BRD-K82823804 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2485 BRD-K82823804 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42150 BRD-K82823804 A549 10 uM 6 h -0.21 -0.86 0.02 -0.51 -1.71 15.65
42485 BRD-K82823804 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42795 BRD-K82823804 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43087 BRD-K82823804 HT29 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
43359 BRD-K82823804 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43660 BRD-K82823804 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44212 BRD-K82823804 SKB 10 uM 24 h -0.24 -1.0 0.15 -0.26 -0.89 0.27
97272 BRD-K82823804 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97352 BRD-K82823804 A375 0.66 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).