CMap Candidate Details
Structure:
| CMap ID: | C04078 |
| Pert ID: | BRD-K55034111 |
| Compound Name: | pefloxacin |
| Targets: | TOP2A |
| MoA: | bacterial DNA gyrase inhibitor |
| SMILES: | CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(C)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24453 | BRD-K55034111 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.15 |
| 24588 | BRD-K55034111 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24789 | BRD-K55034111 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24921 | BRD-K55034111 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.73 | 0.05 |
| 25170 | BRD-K55034111 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25390 | BRD-K55034111 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51618 | BRD-K55034111 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91332 | BRD-K55034111 | HUH7 | 10 uM | 72 h | 0.3 | 1.27 | 0.58 | 0.0 | 0.0 | 0.0 |
| 99666 | BRD-K55034111 | U2OS | 10 uM | 6 h | 0.21 | 0.86 | 0.01 | 0.29 | 1.04 | 0.56 |