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CMap Candidate Details

Structure:
CMap ID: C04085
Pert ID: BRD-K47780086
Compound Name: penciclovir
Targets:
MoA: DNA directed DNA polymerase inhibitor
SMILES: Nc1nc(O)c2ncn(CCC(CO)CO)c2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25514 BRD-K47780086 VCAP 10 uM 6 h -0.27 -1.13 0.4 0.0 0.0 0.0
91334 BRD-K47780086 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
125314 BRD-K47780086 HEK293 1.11 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
125446 BRD-K47780086 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125495 BRD-K47780086 PC3 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
125518 BRD-K47780086 THP1 0.37 uM 24 h 0.24 1.01 0.12 -0.24 -0.8 0.12
133340 BRD-K47780086 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133365 BRD-K47780086 A549 0.74 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
133390 BRD-K47780086 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
133423 BRD-K47780086 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133456 BRD-K47780086 HT29 0.25 uM 24 h 0.23 0.96 0.07 -0.18 -0.62 0.0
133485 BRD-K47780086 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133519 BRD-K47780086 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133554 BRD-K47780086 MDAMB231 2.22 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
133633 BRD-K47780086 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).