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CMap Candidate Details

Structure:
CMap ID: C04086
Pert ID: BRD-K15409150
Compound Name: penfluridol
Targets: CACNA1G
MoA: T-type calcium channel blocker
SMILES: OC1(CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccc(Cl)c(c1)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4199 BRD-K15409150 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4375 BRD-K15409150 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9681 BRD-K15409150 H1299 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11271 BRD-K15409150 MCF??7.00 30 uM 6 h 0.0 0.0 0.0 -0.48 -1.61 15.65
13590 BRD-K15409150 VCAP 30 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37128 BRD-K15409150 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37603 BRD-K15409150 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37877 BRD-K15409150 HEPG2 10 uM 6 h -0.23 -0.94 0.08 -0.44 -1.49 15.35
38059 BRD-K15409150 HT29 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
38917 BRD-K15409150 SKB 10 uM 24 h 0.19 0.78 0.0 -0.3 -1.01 0.58
122340 BRD-K15409150 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122378 BRD-K15409150 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.52
122452 BRD-K15409150 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122501 BRD-K15409150 THP1 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
122530 BRD-K15409150 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130574 BRD-K15409150 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130645 BRD-K15409150 HEK293 0.01 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
130801 BRD-K15409150 MDAMB231 0.08 uM 24 h -0.24 -1.02 0.17 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).