CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04089
Pert ID:	BRD-K43966364
Compound Name:	penicillin-v-potassium
Targets:
MoA:	bacterial cell wall synthesis inhibitor
SMILES:	CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
52836	BRD-K43966364	HEPG2	1.25 uM	24 h	0.18	0.73	0.0	0.0	0.0	0.0
53361	BRD-K43966364	MCF10A	30 uM	24 h	0.0	0.0	0.0	-0.32	-1.09	0.84
95359	BRD-K43966364	MCF??7.00	1.11 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
95418	BRD-K43966364	U2OS	0.12 uM	48 h	-0.23	-0.95	0.09	0.23	0.81	0.09
123253	BRD-K43966364	A375	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123284	BRD-K43966364	HA1E	3.33 uM	24 h	0.21	0.87	0.01	0.25	0.89	0.21
123407	BRD-K43966364	MDAMB231	0.125 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.55
123442	BRD-K43966364	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131568	BRD-K43966364	A549	0.01 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.67
131646	BRD-K43966364	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131673	BRD-K43966364	HELA	0.03 uM	24 h	0.29	1.22	0.48	-0.18	-0.61	0.0
131696	BRD-K43966364	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131805	BRD-K43966364	JURKAT	0.08 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
131944	BRD-K43966364	THP1	0.08 uM	24 h	0.0	0.0	0.0	-0.39	-1.3	1.57
131963	BRD-K43966364	YAPC	2.22 uM	24 h	0.19	0.8	0.0	0.19	0.67	0.01

Summary