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CMap Candidate Details

Structure:
CMap ID: C04092
Pert ID: BRD-K13183738
Compound Name: pentamidine
Targets: TRDMT1
MoA: anti-pneumocystis agent
SMILES: NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
53388 BRD-K13183738 HEPG2 2.5 uM 24 h -0.21 -0.87 0.02 -0.44 -1.48 15.35
53500 BRD-K13183738 HUH7 10 uM 24 h -0.29 -1.19 0.53 0.0 0.0 0.0
53645 BRD-K13183738 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90796 BRD-K13183738 HPTEC 320 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122248 BRD-K13183738 A375 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.47
122297 BRD-K13183738 HA1E 10 uM 24 h -0.3 -1.25 0.71 -0.31 -1.05 0.69
122314 BRD-K13183738 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
122343 BRD-K13183738 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122358 BRD-K13183738 MCF10A 1.11 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
122388 BRD-K13183738 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122416 BRD-K13183738 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
122437 BRD-K13183738 PC3 1.11 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
122471 BRD-K13183738 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122514 BRD-K13183738 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130552 BRD-K13183738 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130663 BRD-K13183738 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).