CMap Candidate Details
Structure:
| CMap ID: | C04122 |
| Pert ID: | BRD-K31519811 |
| Compound Name: | PF-02545920 |
| Targets: | PDE10A |
| MoA: | phosphodiesterase inhibitor |
| SMILES: | Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1468 | BRD-K31519811 | NPC | 10 uM | 24 h | 0.25 | 1.06 | 0.19 | 0.0 | 0.0 | 0.0 |
| 96723 | BRD-K31519811 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96772 | BRD-K31519811 | PC3 | 10 uM | 24 h | -0.21 | -0.86 | 0.02 | 0.0 | 0.0 | 0.0 |
| 121922 | BRD-K31519811 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121939 | BRD-K31519811 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121966 | BRD-K31519811 | HEK293 | 10 uM | 24 h | 0.21 | 0.88 | 0.02 | -0.25 | -0.84 | 0.18 |
| 122018 | BRD-K31519811 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122065 | BRD-K31519811 | HUVEC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122092 | BRD-K31519811 | MCF10A | 10 uM | 24 h | -0.28 | -1.15 | 0.44 | 0.0 | 0.0 | 0.0 |
| 122116 | BRD-K31519811 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.4 | -1.34 | 1.86 |
| 122149 | BRD-K31519811 | MDAMB231 | 10 uM | 24 h | -0.17 | -0.69 | 0.0 | 0.35 | 1.24 | 1.26 |
| 122202 | BRD-K31519811 | THP1 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130299 | BRD-K31519811 | HELA | 2.22 uM | 24 h | -0.19 | -0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130366 | BRD-K31519811 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130533 | BRD-K31519811 | YAPC | 2.22 uM | 24 h | 0.27 | 1.14 | 0.32 | 0.0 | 0.0 | 0.0 |