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CMap Candidate Details

Structure:
CMap ID: C04217
Pert ID: BRD-K76568384
Compound Name: PHTPP
Targets: ESR2
MoA: estrogen receptor antagonist
SMILES: Oc1ccc(cc1)-c1c(nn2c(cc(nc12)C(F)(F)F)C(F)(F)F)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1624 BRD-K76568384 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
1970 BRD-K76568384 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2271 BRD-K76568384 PC3 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
2751 BRD-K76568384 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41840 BRD-K76568384 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.42
42145 BRD-K76568384 A549 10 uM 6 h -0.18 -0.77 0.0 0.0 0.0 0.0
42472 BRD-K76568384 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42782 BRD-K76568384 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
43076 BRD-K76568384 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43356 BRD-K76568384 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43649 BRD-K76568384 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43949 BRD-K76568384 PHH 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
99479 BRD-K76568384 U2OS 10 uM 6 h 0.23 0.96 0.07 -0.23 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).