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CMap Candidate Details

Structure:
CMap ID: C04223
Pert ID: BRD-K97365803
Compound Name: PI-828
Targets:
MoA: PI3K inhibitor
SMILES: Nc1ccc(cc1)-c1cccc2c1oc(cc2=O)N1CCOCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1799 BRD-K97365803 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2152 BRD-K97365803 HCC515 10 uM 6 h 0.0 0.0 0.0 0.38 1.34 1.72
2454 BRD-K97365803 PC3 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
2497 BRD-K97365803 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
39252 BRD-K97365803 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39385 BRD-K97365803 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39867 BRD-K97365803 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40152 BRD-K97365803 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40411 BRD-K97365803 HT29 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
40553 BRD-K97365803 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
41286 BRD-K97365803 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41630 BRD-K97365803 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95980 BRD-K97365803 PHH 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).