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CMap Candidate Details

Structure:
CMap ID: C04230
Pert ID: BRD-K01029106
Compound Name: picolinic-acid
Targets:
MoA: chelating agent
SMILES: O=C(O[Cr](OC(=O)c1ccccn1)OC(=O)c1ccccn1)c1ccccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122830 BRD-K01029106 A375 3.33 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
122886 BRD-K01029106 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122966 BRD-K01029106 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123011 BRD-K01029106 JURKAT 1.11 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
123058 BRD-K01029106 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
123100 BRD-K01029106 MDAMB231 0.04 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
123172 BRD-K01029106 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131237 BRD-K01029106 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
131274 BRD-K01029106 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131300 BRD-K01029106 HELA 0.01 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
131348 BRD-K01029106 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131430 BRD-K01029106 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
131458 BRD-K01029106 PC3 0.74 uM 24 h 0.23 0.97 0.08 0.34 1.2 1.09
131488 BRD-K01029106 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).