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CMap Candidate Details

Structure:
CMap ID: C04269
Pert ID: BRD-K16277217
Compound Name: piperacetazine
Targets:
MoA: dopamine receptor antagonist
SMILES: CC(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CCO)CC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1560 BRD-K16277217 HA1E 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
2089 BRD-K16277217 HCC515 10 uM 6 h 0.26 1.08 0.21 0.23 0.81 0.09
2189 BRD-K16277217 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2678 BRD-K16277217 VCAP 10 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
41738 BRD-K16277217 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42071 BRD-K16277217 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.08
42314 BRD-K16277217 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42645 BRD-K16277217 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42949 BRD-K16277217 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43302 BRD-K16277217 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
43505 BRD-K16277217 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44081 BRD-K16277217 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).