CMap Candidate Details
Structure:
| CMap ID: | C04274 |
| Pert ID: | BRD-A97479839 |
| Compound Name: | piperidolate |
| Targets: | CHRM1 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | CCN1CCCC(C1)OC(=O)C(c1ccccc1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5566 | BRD-A97479839 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6357 | BRD-A97479839 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39421 | BRD-A97479839 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.17 | 0.92 |
| 39615 | BRD-A97479839 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 39935 | BRD-A97479839 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40740 | BRD-A97479839 | NEU | 10 uM | 24 h | -0.27 | -1.11 | 0.37 | 0.0 | 0.0 | 0.0 |
| 41041 | BRD-A97479839 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 41365 | BRD-A97479839 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.17 | 0.92 |
| 52111 | BRD-A97479839 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.45 | 15.35 |
| 99934 | BRD-A97479839 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.19 |
| 128411 | BRD-A97479839 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128463 | BRD-A97479839 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128518 | BRD-A97479839 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.94 |
| 128573 | BRD-A97479839 | JURKAT | 0.04 uM | 24 h | 0.3 | 1.26 | 0.56 | 0.27 | 0.97 | 0.35 |
| 128665 | BRD-A97479839 | MDAMB231 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128744 | BRD-A97479839 | THP1 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128783 | BRD-A97479839 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.15 |
| 136201 | BRD-A97479839 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136278 | BRD-A97479839 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136323 | BRD-A97479839 | MCF10A | 0.03 uM | 24 h | 0.22 | 0.9 | 0.02 | 0.22 | 0.79 | 0.07 |
| 136375 | BRD-A97479839 | PC3 | 0.01 uM | 24 h | 0.17 | 0.71 | 0.0 | 0.0 | 0.0 | 0.0 |