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CMap Candidate Details

Structure:
CMap ID: C04374
Pert ID: BRD-A78391468
Compound Name: prednisolone-hemisuccinate
Targets: NR3C1
MoA: glucocorticoid receptor agonist
SMILES: C[C@]12C[C@H](O)C3C(CCC4=CC(=O)C=C[C@]34C)C1CC[C@]2(O)C(=O)COC(=O)CCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5282 BRD-A78391468 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5738 BRD-A78391468 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.92
6152 BRD-A78391468 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6491 BRD-A78391468 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37105 BRD-A78391468 A375 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
37254 BRD-A78391468 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37553 BRD-A78391468 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
37854 BRD-A78391468 HEPG2 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
38040 BRD-A78391468 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
38169 BRD-A78391468 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
38395 BRD-A78391468 NPC 10 uM 24 h -0.22 -0.9 0.04 -0.35 -1.17 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).