CMap Candidate Details
Structure:
| CMap ID: | C04386 |
| Pert ID: | BRD-A53952395 |
| Compound Name: | prilocaine |
| Targets: | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A |
| MoA: | local anesthetic |
| SMILES: | CCCNC(C)C(=O)Nc1ccccc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49770 | BRD-A53952395 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 49950 | BRD-A53952395 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 50112 | BRD-A53952395 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.88 |
| 50299 | BRD-A53952395 | HCC515 | 10 uM | 6 h | -0.3 | -1.24 | 0.64 | 0.0 | 0.0 | 0.0 |
| 50464 | BRD-A53952395 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50716 | BRD-A53952395 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50807 | BRD-A53952395 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51101 | BRD-A53952395 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 100216 | BRD-A53952395 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.18 |