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CMap Candidate Details

Structure:
CMap ID: C04396
Pert ID: BRD-K72029282
Compound Name: probucol
Targets: ABCA1|ABCB11|CES1
MoA: atherogenesis inhibitor
SMILES: CC(C)(Sc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)Sc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3254 BRD-K72029282 HCC515 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
3853 BRD-K72029282 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
45013 BRD-K72029282 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45305 BRD-K72029282 HEPG2 10 uM 6 h -0.17 -0.72 0.0 0.26 0.92 0.25
46127 BRD-K72029282 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
46441 BRD-K72029282 PHH 10 uM 24 h 0.32 1.32 0.82 0.0 0.0 0.0
46766 BRD-K72029282 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126636 BRD-K72029282 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126657 BRD-K72029282 A549 0.125 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
126699 BRD-K72029282 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126726 BRD-K72029282 HELA 0.125 uM 24 h -0.22 -0.93 0.07 -0.26 -0.87 0.22
126749 BRD-K72029282 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126811 BRD-K72029282 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
126854 BRD-K72029282 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
126898 BRD-K72029282 MDAMB231 1.11 uM 24 h 0.3 1.25 0.53 0.0 0.0 0.0
126966 BRD-K72029282 THP1 0.125 uM 24 h -0.25 -1.03 0.19 0.27 0.97 0.34
134740 BRD-K72029282 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
134880 BRD-K72029282 HUVEC 0.74 uM 24 h -0.24 -0.98 0.12 0.0 0.0 0.0
134906 BRD-K72029282 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134970 BRD-K72029282 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134998 BRD-K72029282 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).