CMap Candidate Details
Structure:
| CMap ID: | C04453 |
| Pert ID: | BRD-K16757695 |
| Compound Name: | PRX-08066 |
| Targets: | HTR2B |
| MoA: | serotonin receptor antagonist |
| SMILES: | Fc1ccc(CN2CCC(CC2)Nc2ncnc3sc(Cl)cc23)cc1C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120242 | BRD-K16757695 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120279 | BRD-K16757695 | A549 | 10 uM | 24 h | 0.27 | 1.14 | 0.32 | 0.0 | 0.0 | 0.0 |
| 120342 | BRD-K16757695 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 120378 | BRD-K16757695 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120406 | BRD-K16757695 | MCF??7.00 | 10 uM | 24 h | -0.2 | -0.85 | 0.01 | 0.0 | 0.0 | 0.0 |
| 120437 | BRD-K16757695 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120475 | BRD-K16757695 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128905 | BRD-K16757695 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |