CMap Candidate Details
Structure:
| CMap ID: | C04474 |
| Pert ID: | BRD-K41564320 |
| Compound Name: | purvalanol-b |
| Targets: | CDK2|CDK4|CDK5|MAPK1|MAPK3|SRPK2 |
| MoA: | tyrosine kinase inhibitor |
| SMILES: | CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c2ncn(C(C)C)c2n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6749 | BRD-K41564320 | A375 | 10 uM | 24 h | -0.24 | -1.02 | 0.18 | 0.0 | 0.0 | 0.0 |
| 6995 | BRD-K41564320 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7318 | BRD-K41564320 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7863 | BRD-K41564320 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8172 | BRD-K41564320 | MCF??7.00 | 10 uM | 6 h | 0.24 | 0.98 | 0.09 | -0.31 | -1.04 | 0.67 |
| 8506 | BRD-K41564320 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.64 | 0.01 |
| 8815 | BRD-K41564320 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.16 | 1.11 |