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CMap Candidate Details

Structure:
CMap ID: C04478
Pert ID: BRD-K62277907
Compound Name: PYM50028
Targets:
MoA: neurotrophic agent
SMILES: C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@]11CC[C@H](C)CO1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124927 BRD-K62277907 A375 0.02 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
124953 BRD-K62277907 A549 0.2 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125015 BRD-K62277907 HELA 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125046 BRD-K62277907 HT29 0.02 uM 24 h 0.24 0.99 0.1 -0.28 -0.95 0.39
125066 BRD-K62277907 MCF10A 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125144 BRD-K62277907 THP1 1.67 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
125195 BRD-K62277907 YAPC 0.06 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
133005 BRD-K62277907 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133030 BRD-K62277907 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133214 BRD-K62277907 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
133252 BRD-K62277907 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133279 BRD-K62277907 PC3 0.004 uM 24 h 0.25 1.06 0.19 0.32 1.15 0.88
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).