CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00450
Pert ID:	BRD-K11433652
Compound Name:	aspirin
Targets:	AKR1C1\|ASIC3\|EDNRA\|HSPA5\|IKBKB\|NFKB1\|NFKB2\|NFKBIA\|PRKAA1\|PRKAA2\|PRKAB1\|PRKAB2\|PRKAG1\|PRKAG2\|PRKAG3\|PTGS1\|PTGS2\|RPS6KA3\|TP53
MoA:	cyclooxygenase inhibitor
SMILES:	CC(=O)Oc1ccccc1C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
50340	BRD-K11433652	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
51010	BRD-K11433652	VCAP	10 uM	24 h	-0.16	-0.68	0.0	0.22	0.78	0.07
52588	BRD-K11433652	A549	6.66 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
52897	BRD-K11433652	HEPG2	40 uM	24 h	0.0	0.0	0.0	-0.28	-0.93	0.34
53100	BRD-K11433652	MCF10A	100 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
90795	BRD-K11433652	HPTEC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
91306	BRD-K11433652	HUH7	20 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
121171	BRD-K11433652	A375	0.04 uM	24 h	-0.25	-1.06	0.25	0.0	0.0	0.0
121273	BRD-K11433652	HELA	10 uM	3 h	0.19	0.8	0.0	0.0	0.0	0.0
121298	BRD-K11433652	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129259	BRD-K11433652	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129319	BRD-K11433652	HT29	0.08 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.73
129359	BRD-K11433652	PC3	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129392	BRD-K11433652	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary