CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04531
Pert ID:	BRD-K54665485
Compound Name:	R-59022
Targets:	DGKA
MoA:	diacylglycerol kinase inhibitor; protein kinase inhibitor
SMILES:	Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccccc1)c1ccc(F)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6781	BRD-K54665485	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7012	BRD-K54665485	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7343	BRD-K54665485	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7892	BRD-K54665485	HT29	10 uM	24 h	0.21	0.86	0.01	0.32	1.14	0.86
8285	BRD-K54665485	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8393	BRD-K54665485	PC3	10 uM	24 h	0.23	0.98	0.09	0.33	1.15	0.9
8705	BRD-K54665485	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99659	BRD-K54665485	U2OS	10 uM	6 h	0.0	0.0	0.0	0.26	0.91	0.23

Summary