CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04535
Pert ID:	BRD-A08187463
Compound Name:	racecadotril
Targets:	MME
MoA:	enkephalinase inhibitor
SMILES:	CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4003	BRD-A08187463	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.78
4272	BRD-A08187463	HCC515	10 uM	24 h	-0.27	-1.12	0.38	0.29	1.01	0.46
4833	BRD-A08187463	VCAP	10 uM	24 h	0.25	1.04	0.14	0.0	0.0	0.0
37437	BRD-A08187463	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37781	BRD-A08187463	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38291	BRD-A08187463	NPC	10 uM	24 h	-0.19	-0.78	0.0	0.0	0.0	0.0
38600	BRD-A08187463	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38816	BRD-A08187463	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91409	BRD-A08187463	HUH7	8 uM	72 h	-0.26	-1.08	0.3	0.0	0.0	0.0
121142	BRD-A08187463	A375	0.04 uM	24 h	0.0	0.0	0.0	-0.22	-0.74	0.05
121178	BRD-A08187463	A549	0.04 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
121246	BRD-A08187463	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121286	BRD-A08187463	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.32	1.14	0.87
121303	BRD-A08187463	PC3	0.125 uM	24 h	0.18	0.77	0.0	0.31	1.1	0.7
129287	BRD-A08187463	HT29	0.25 uM	24 h	0.0	0.0	0.0	-0.23	-0.77	0.08
129360	BRD-A08187463	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.72

Summary