CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04539
Pert ID:	BRD-K84683831
Compound Name:	radezolid
Targets:
MoA:	bacterial 30S ribosomal subunit inhibitor; bacterial 50S ribosomal subunit inhibitor
SMILES:	CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95345	BRD-K84683831	MCF??7.00	10 uM	24 h	0.26	1.07	0.2	0.23	0.8	0.08
95388	BRD-K84683831	U2OS	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125967	BRD-K84683831	A375	10 uM	24 h	0.0	0.0	0.0	0.2	0.69	0.01
125986	BRD-K84683831	A549	10 uM	24 h	0.22	0.91	0.04	-0.28	-0.94	0.38
126034	BRD-K84683831	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126091	BRD-K84683831	HUVEC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126139	BRD-K84683831	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126192	BRD-K84683831	MCF10A	0.37 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.75
126242	BRD-K84683831	MDAMB231	10 uM	24 h	-0.23	-0.96	0.1	-0.28	-0.95	0.41
126310	BRD-K84683831	THP1	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.17	1.12
134072	BRD-K84683831	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134187	BRD-K84683831	HT29	2.22 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.73
134290	BRD-K84683831	PC3	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134321	BRD-K84683831	YAPC	0.74 uM	24 h	0.0	0.0	0.0	0.35	1.23	1.24

Summary