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CMap Candidate Details

Structure:
CMap ID: C04547
Pert ID: BRD-K89348303
Compound Name: ramipril
Targets: ACE
MoA: angiotensin converting enzyme inhibitor
SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25441 BRD-K89348303 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50429 BRD-K89348303 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91413 BRD-K89348303 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
127732 BRD-K89348303 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127774 BRD-K89348303 A549 0.37 uM 24 h 0.3 1.26 0.58 0.0 0.0 0.0
127852 BRD-K89348303 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127926 BRD-K89348303 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
127980 BRD-K89348303 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128023 BRD-K89348303 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
135523 BRD-K89348303 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135553 BRD-K89348303 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135601 BRD-K89348303 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135644 BRD-K89348303 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135714 BRD-K89348303 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135737 BRD-K89348303 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).